What Industrial & Pharma Uses Does High-Purity 5-Isobutyl Hydantoin Provide?

High-purity hydantoin intermediates are core raw materials for drug synthesis, green agrochemicals and functional polymer production. 5-Isobutyl Hydantoin (CAS 616-04-6) manufactured by Leache Chem is white crystalline powder with ≥99.5 purity, stable chemical index and wide compatibility with various synthesis reactions.

1. Basic Introduction To 5-Isobutyl Hydantoin

5-Isobutyl Hydantoin carries CAS number 616-04-6, a classic hydantoin-series pharmaceutical intermediate independently mass-produced by Leache Chem for more than 25 years. The product presents white crystalline powder with steady melting point and low moisture content, which can participate in chiral drug synthesis, PROTAC material preparation and green agrochemical development. As China’s earliest hydantoin manufacturer founded in 1972, Leache controls strict production process to guarantee purity above 99.5%, effectively reducing side reactions during downstream synthesis and lowering production loss for end manufacturers.

2. Full Physical & Chemical Specification 

3. Multi-Industry Application Fields

Pharmaceutical Industry (Core Application)

1. Raw material for high-value API and chiral compound synthesis

2. CRBN ligand carrier for PROTAC anticancer drug design

3. Medical coating antibacterial material to inhibit biofilm growth

4. Precursor of neurological targeted medicines with high metabolic stability

Agrochemical Industry

Green synthesis building block for environment-friendly crop protection agents, matching low-toxicity agricultural formulation standards.

New Material & Industrial Field

1. Raw material for anti-corrosion coatings and metal corrosion inhibitors

2. Monomer of bio-based degradable specialty polymers

3. Functional additive for advanced electrolyte systems

4. Standard & Custom Packaging Solutions

All 5-Isobutyl Hydantoin adopts double-layer anti-leak packaging to keep chemical stability during long-distance sea and land transport:

1. Inner package: Food-grade PE plastic liner to isolate moisture

2. Outer package: UV-proof woven polypropylene bag to avoid light damage

Standard packing specifications:

• 25kg sealed plastic drum for small batch lab orders

• 500kg FIBC bulk jumbo bag for factory mass production

Custom support: Adjust bag weight, outer label, logo and carton printing according customer brand demands.

5. Leache Chem Technical Strength

Leache Chem was established in Handan, Hebei in 1972, the first domestic enterprise specialized in hydantoin series R&D and manufacturing:

1. Enterprise Qualifications: National High-Tech Enterprise, Hebei Grade A R&D Institution, multiple synthesis reaction patents

2. Production Capacity: Independent pilot workshop supporting bromination, chlorination and cyanation customized synthesis; 25-year mature production line of 5-Isobutyl Hydantoin

3. Global Market: Products sold to over 50 countries; hydantoin intermediates occupy over 50% market share in Europe and America

4. Product Line Layout: Hydantoin series, thiophene intermediates, bromine disinfectants and other fine chemical raw materials

5. QC System: Full-process online index detection to strictly control purity and moisture of finished powder

6. Complete Pre-Sales & After-Sales Service

Pre-Sales

1. Free sample supply for laboratory testing

2. Custom synthesis development according customer reaction formula

3. Provide complete COA test report before order confirmation

4. Factory video inspection or offline plant visit arrangement

In-Sales

1. Flexible batch support from small lab trial to industrial bulk tonnage

2. Custom packaging, label and brand printing service

3. Real-time production progress update during manufacturing

After-Sales

1. Professional technical team provides synthesis guidance

2. Timely handling of product index consultation and complaint feedback

3. Stable long-term supply contract for pharmaceutical and agrochemical manufacturers

7. Customer FAQ

Q1 What is the CAS number of Leache 5-Isobutyl Hydantoin?

A The CAS No. is 616-04-6, all batch COA documents clearly mark this standard code.

Q2 What is the minimum purity of your 5-Isobutyl Hydantoin?

A Our standard finished product purity reaches ≥99.5%, much higher than general industrial grade intermediates.

Q3 Can I customize packaging labels and outer logos?

A Yes, we support personalized packaging design, printing brand information on drums and jumbo bags.

Q4 Is this intermediate suitable for PROTAC anticancer drug synthesis?

A Yes, its stable hydantoin structure acts as classic CRBN ligand raw material widely used in new drug R&D.

Q5 What delivery cycle for bulk ton orders?

We maintain sufficient raw material inventory, mass goods can be delivered within short lead time after deposit confirmation.

Q6 Can you provide COA and quality inspection documents?

A Each batch of 5-Isobutyl Hydantoin comes with complete test certificate for customs and factory filing.

Summary & Cooperation Invitation

5-Isobutyl Hydantoin is a multi-functional fine chemical intermediate indispensable for pharmaceutical R&D, green agrochemical and new polymer industries. Leache Chem relies on nearly 50 years of hydantoin production experience, independent pilot R&D workshop and strict quality control system to supply high-purity stable 5-Isobutyl Hydantoin to global buyers. Whether you need lab small trial samples, ton-level bulk procurement or exclusive customized synthesis raw materials, we can provide accurate COA reports, reasonable quotations and stable long-term supply plans. If you want to know more about chemical indexes, synthesis application cases and customized packaging schemes, please feel free to contact us. Our professional fine chemical technical sales team will offer targeted raw material solutions for your research and production projects.